Toxicity Estimation of Phenolic Compounds by Bioluminescent Bacterium
Publication: Journal of Environmental Engineering
Volume 129, Issue 4
Abstract
Phenolic compounds are environmentally important due to their extensive use in various industries, presence in wastewaters, and potential toxicity. When phenolic compounds reach the activated sludge processes of publicly owned treatment works, they can cause upsets in the operations of the treatment plants. A continuous toxicity testing system was developed based on the bioluminescent bacterium Shk1. The toxicities of 23 phenolic compounds to Shk1 were studied and the 5 min values were obtained. Quantitative structure-activity relationship models based on the logarithm of the octanol-water partitioning coefficient were established for estimating the toxicity of phenolic compounds and the model validity was verified.
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References
Akers, K. S., Sinks, G. D., and Schultz, T. W.(1998). “Structure-toxicity relationships for selected halogenated aliphatic chemicals.” Environ. Toxicol. Pharmacol.,7(1), 33–39.
Albert, A. (1979). Selective toxicity, Chapman and Hall, London.
Arcand, Y. A., Hawari, J., and Guiot, S. R.(1995). “Solubility of pentachlorophenol in aqueous solutions: The pH effect.” Water Res., 29(1), 131–136.
Blum, D. J. W. (1989). “Chemical toxicity to environmental bacteria: Quantitative structure-activity relationships and interspecies correlations and comparison.” PhD dissertation, Drexel Univ., Philadelphia.
Blum, D. J. W., and Speece, R. E.(1991). “A database of chemical toxicity to environmental bacteria and its use in interspecies comparisons and correlation.” Res. J. Water Pollut. Control Fed., 63(3), 198–207.
Blum, D. J. W., and Speece, R. E.(1992). “The toxicity of organic chemicals to treatment processes.” Water Sci. Technol., 25(3), 23–31.
Bradbury, S. P., and Lipnick, R. L.(1990). “Introduction: Structural properties for determining mechanisms of toxic action.” Environ. Health Perspect., 87, 181–182.
Caza, N., Bewtra, J. K., Biswas, N., and Taylor, K. E.(1999). “Removal of phenolic compounds from synthetic wastewater using soybean proxidase.” Water Res., 33(13), 3012–3018.
Chapoteau, E., Czech, B. P., Kumar, A., Pose, A., Bartsch, R. A., Holwerda, R. A., Dalley, K. N., Wilson, B. E., and Weining, J.(1989). “Synthesis, structures, and complexing abilities of corands based on 2-methoxyresorcinol.” J. Org. Chem., 54(4), 861–867.
Chen, S. T., Dong, J., Berthouex, P. M., and Boyle, W. C.(2000). “Fate of pentachlorophenol (PCP) in an anaerobic digester.” Water Environ. Res., 72(2), 201–206.
Clements, R. G., Nabholz, J. V., Zeeman, M. G., and Auer, C. M.(1995). “The application of structure-activity relationships (SARs) in the aquatic toxicity evaluation of discrete organic chemicals.” SAR QSAR Environ. Res., 3(3), 203–215.
Cronin, M. T. D., and Dearden, J. C.(1995). “Review: QSAR in toxicology. 1. Prediction of aquatic toxicity.” Quant. Struct.-Act. Relat.,14(1), 1–7.
Cronin, M. T. D., and Schultz, T. W. (2003). “Pitfalls in QSAR.” J. Mol. Struct.: THEOCHEM, in press.
Cros, A. F. A. (1863). “Action de l’alcohol amylique sur l’organisme.” Thesis, Univ. of Strasbourg, Strasbourg, France.
Dearden, J. C.(1985). “Partitioning and lipophilicity in quantitative structure-activity relationships.” Environ. Health Perspect., 61, 203–228.
Dean, J. (1985). Lange’s handbook of chemistry, 13th Ed., McGraw-Hill, New York.
DeWeese, A., and Schultz, T. W.(2001). “Structure-activity relationships for aquatic toxicity to Tetrahymena: Halogen-substituted aliphatic esters.” Environ. Toxicol.,16(1), 54–60.
Dutka, B. J., and Kwan, K. K. (1984). “Studies on a synthetic activated sludge toxicity screening procedure with comparison to three microbial toxicity tests.” Toxicity screening procedures using bacterial systems, D. Liu and B. J. Dutka, eds., Marcel Dekker, New York, 125–138.
Elnabarawy, M. T., Robideau, R. R., and Beach, S. A.(1988). “Comparison of three rapid toxicity test procedures: Microtox, Polytox, and activated sludge respiration inhibition.” Tox. Assess.,3, 361–370.
Fang, H. H. P., Chen, T., Li, Y. Y., and Chui, H. K.(1996). “Degradation of phenol in wastewater in an upflow anaerobic sludge blanket reactor.” Water Res., 30(6), 1353–1360.
Fochtman, P., Raszka, A., and Nierzedska, E.(2000). “The use of conventional bioassays, microbiotests, and some ‘rapid’ methods in the selection of an optimal test battery for the assessment of pesticides toxicity.” Environ. Toxicol.,15(5), 376–384.
Goutte, C.(1997). “Note on free lunches and cross-validation.” Neural Comput., 9(6), 1211–1215.
Hall, E., Sun, B., Prakash, J., and Nirmalakhandan, N.(1996). “Toxicity of organic chemicals and their mixtures to activated sludge microorganisms.” J. Environ. Eng., 122(5), 424–429.
Hansch, C., and Leo, A. (1979). Substituent constants for correlation analysis in chemistry and biology, Wiley, New York.
Harrell, F. E., Jr. (2001). Regression modeling strategies, Springer, New York.
Hoffmann, C., and Christofi, N.(2001). “Testing the toxicity of influents to activated sludge plants with the Vibrio fischeri bioassay utilizing a sludge matrix.” Environ. Toxicol.,16(5), 422–427.
Kahru, A., Kurvet, M., and Külm, I.(1996). “Toxicity of phenolic wastewater to luminescent bacteria Photobacterium phosphoreum and activated sludge.” Water Res., 33(6), 139–146.
Kahru, A., Põllumaa, L., Reiman, R., Rätsep, A., Liiders, M., and Maloveryan, A.(2000). “The toxicity and biodegradability of eight main phenolic compounds characteristic to the oil-shale industry wastewaters: A test battery approach.” Environ. Toxicol.,15(4), 431–442.
Kelly, C. J., Lajoie, C. A., Layton, A. C., and Sayler, G. S.(1999). “Bioluminescence reporter bacterium for toxicity monitoring in biological wastewater treatment systems.” Water Environ. Res., 71(1), 31–35.
Kirk, R. E., and Othemer, D. F. (1978). Encyclopedia of chemical technology, 3rd Ed., Wiley Interscience, New York.
Kollig, H. P. (1993). Environmental fate constants for organic chemicals under consideration for EPA’s hazardous waste identification projects, Office of Research and Development, EPA, Washington, D.C.
Kong, Z., Vanrolleghem, P. A., and Verstraete, W.(1993). “An activated sludge-based biosensor for rapid estimation and on-line toxicity monitoring.” Biosens. Bioelectron., 8(1), 49–58.
Kortum, G., Vogel, W., and Andrussow, K. (1961). Dissociation constants of organic acids in aqueous solution, Butterworths, London.
Lanouette, K. H.(1977). “Treatment of phenolic wastes.” Chem. Eng., 84(22), 99–106.
Lee, L. S., Rao, P. S. C., and Brusseau, M. L.(1991). “Nonequilibrium sorption and transport of neutral and ionized compounds.” Environ. Sci. Technol., 25(4), 722–729.
MacKay, D., Shiu, W. Y., and Ma, K. C. (1992). Illustrated handbook of physical-chemical properties and environmental fate for organic chemicals, Lewis, Boca Raton, Fla.
McLeease, D. W., Zitko, V., and Peterson, M. R.(1979). “Structure-lethality relationships for phenols, anilines and other aromatic compounds in shrimp and clams.” Chemosphere, 8(2), 53–57.
Ren, S. (2001). “Development of a continuous bioluminescent bacteria-based system for POTW influent wastewater toxicity monitoring.” PhD dissertation, Univ. of Tennessee, Knoxville, Tenn.
Rozich, A. G., Gaudy, A. F., Jr., and D’Adamo, P. D.(1983). “Predictive model for treatment of phenolic wastes by activated sludge.” Water Res., 17(10), 1453–1466.
Rozich, A. G., Gaudy, A. F., Jr., and D’Adamo, P. D.(1985). “Selection of growth rate model activated sludges treating phenol.” Water Res., 19(4), 481–490.
Schultz, T. W., Bearden, A. P., and Jaworska, J. S.(1996). “A novel QSAR approach for estimating toxicity of phenols.” SAR QSAR Environ. Res., 5(2), 99–112.
Schultz, T. W., Sinks, G. D., and Bearden, A. P. (1998). “QSAR in aquatic toxicology: A mechanism of action approach comparing toxic potency to Pimephales promelas, Tetrahymena pyriformis, and Vibrio fischeri.” Comparative QSAR, J. Devillers, ed., Taylor & Francis, London, 51–109.
Serjeant, E. P., and Dempsey, B. (1979). “Ionization constants of organic acids in aqueous solution.” Int. Union of Pure and Applied Chemistry Chemical Data Series No. 23, Pergamon, New York.
Short, T. E.(1974). “Controlling phenols in refinery wastes.” Oil Gas J., 72(47), 119–124.
Tang, N. H., Blum, D. J. W., Nirmalakhandan, N., and Speece, R. E.(1992). “QSAR parameters for toxicity of organic chemicals to Nitrobacter.” J. Environ. Eng., 118(1), 17–37.
Vanrolleghem, P. A., Kong, Z., and Coen, F.(1996). “Full-scale on-line assessment of toxic wastewaters causing change in biodegradation model structure and parameters.” Water Sci. Technol., 33(2), 163–175.
Verharr, H. J. M., Van Leeuwen, C. J., and Hermens, J. L. M.(1992). “Classifying environmental pollutants. 1: Structure-activity relationships for prediction of aquatic toxicity.” Chemosphere, 25(4), 471–491.
Volskay, V. T., Jr., and Leslie Grady, C. P., Jr. (1988). “Toxicity of selected RCRA compounds to activated sludge microorganisms.” J. Water Pollut. Control Fed., 60(10), 1850–1856.
Walker, J. D.(1989). “Effects of chemicals on microorganisms.” J. Water Pollut. Control Fed., 61(6), 1077–1097.
Wang, J., Huang, C. P., and Allen, H. E.(2000). “Surface physical-chemical characteristics of sludge particulates.” Water Environ. Res., 72(5), 545–553.
Weast et al., ed. (1965–1966). Handbook of chemistry and physics, 46th Ed., Chemical Rubber, Cleveland.
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Information
Published In
Journal of Environmental Engineering
Volume 129 • Issue 4 • April 2003
Pages: 328 - 335
Copyright
Copyright © 2003 American Society of Civil Engineers.
History
Received: Jun 29, 2001
Accepted: Dec 12, 2002
Published online: Mar 14, 2003
Published in print: Apr 2003
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