Green Synthesis of Metallic Silver Nanoparticles Using Curculigo orchioides Rhizome Extracts and Evaluation of Its Antibacterial, Larvicidal, and Anticancer Activity
Publication: Journal of Environmental Engineering
Volume 142, Issue 9
Abstract
A rapid method for the synthesis of nanoparticles using Curculigo orchioides rhizome extracts (CoREs) with high level of polyphenols, gamma sterol, and -hexadecanoic acid contents was described. The formation of the silver nanoparticles (AgNPs) was confirmed with surface plasmon resonance using ultraviolet-visible (UV) spectroscopy. The synthesized AgNPs were characterized by X-ray diffractometer (XRD), Fourier transform infrared (FTIR) spectroscopy, field emission scanning electron microscopy (FESEM), and high-resolution transmission electron microscopy (HRTEM). The shape of the synthesized AgNPs was spherical morphology with 15–18 nm size. The boiled rhizome extract mediated AgNPs (CoBAgNPs) exhibited a maximum zone of inhibition against the bacterial strains tested. Larvicidal bioassay confirmed that the CoBAgNPs showed the highest mortality rate against the malarial vectors such as Anopheles subpictus and Culex quinquefasciatus. The in vitro cytotoxicity study indicated that the inhibitory concentration () of CoBAgNPs was 18.86 and for human breast cancer cell line (MDA-MB-231) and Vero cells line, respectively, after 48 h of incubation. The present results clearly suggested that the synthesized metallic silver nanoparticles (CoBAgNPs) could act as potential agent for antibacterial, larvicidal, and anticancer activity.
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Acknowledgments
The authors wish to thank the University Grants Commission (UGC), New Delhi, India, for providing Non Special Assistance Programme-Basic Scientific Research (Non SAP-BSR) Fellowship to carry out this study.
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Published In
Journal of Environmental Engineering
Volume 142 • Issue 9 • September 2016
Copyright
© 2016 American Society of Civil Engineers.
History
Received: Apr 8, 2015
Accepted: Nov 12, 2015
Published online: Feb 23, 2016
Discussion open until: Jul 23, 2016
Published in print: Sep 1, 2016
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