Research Article
Apr 1968
Toxicity Measurements in Activated Sludge
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VIEW THE REPLYAuthors: lugwig Hartmann and Gerhard LaubenbergerAuthor Affiliations
Publication: Journal of the Sanitary Engineering Division
Volume 94, Issue 2
Abstract
Toxicity measurements in activated sludge show that the Michaelis-Menten theory and the theory of enzyme inhibition reveal reproducible data on toxicity and also may reveal, insights into the physiological aspects of toxicity. Thus, it can be shown, that toxicity is complex. It consists of at least two components namely of competitive and noncompetitive inhibition. Some toxic materials tend to have a largely competitive effect, others have a largely noncompetitive effect, resulting either in increase of the Michaelis constant (Km) or in reduction of the maximal activity (Vmax). The effect of the pH is pure noncompetitive inhibition. Sludge age also plays an important role. Increasing sludge age finally results in pure competitive inhibition or noncompetitive inhibition, depending on the nature of the toxic material. This can be proved with copper-sulfate and hexavalent chromium.
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Published In
Journal of the Sanitary Engineering Division
Volume 94 • Issue 2 • April 1968
Pages: 247 - 256
Copyright
© 1968 American Society of Civil Engineers.
History
Published in print: Apr 1968
Published online: Feb 12, 2021
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lugwig Hartmann
Prof. and Head of the Lab. of Bioengineering, Karlsruhe, Technical Univ., Wes Germany
Gerhard Laubenberger
Research fellow, Master of Engrg., Lab. of Bioengi neering, Karlsruhe, Technical Univ., West Germany
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