Research Article
Feb 1978
Optimal Design of Aortic Leaflet Prosthesis
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VIEW THE REPLYAuthors: Dhanjoo N. Ghista, K.B. Chandran, Gautam Ray, and Helmut ReulAuthor Affiliations
Publication: Journal of the Engineering Mechanics Division
Volume 104, Issue 1
Abstract
The design criteria for an optimum prosthetic-aortic leaflet valve are a smooth washout in the valve cusps, minimal leaflet stress, minimal transmembrane pressure for the valve to open, an adequate lifetime (for a given blood-compatible leaflet material's fatigue data). A rigorous design analysis is presented to obtain the prosthetic tri-leaflet aortic valve leaflet's optimum design parameters. Four alternative optimum leaflet geometries are obtained to satisfy the criteria of a smooth washout and minimal leaflet stress. The leaflet thicknesses of these four optimum designs are determined by satisfying the two remaining design criteria for minimal transmembrane opening pressure and adequate fatigue lifetime, which are formulated in terms of the elastic and fatigue properties of the selected leaflet material - Avcothane-51 (of the Avco-Everett Co. of Massachusetts). Prosthetic valves are fabricated on the basis of the optimum analysis and the resulting detailed engineering drawings of the designs are also presented in the paper.
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Published In
Journal of the Engineering Mechanics Division
Volume 104 • Issue 1 • February 1978
Pages: 97 - 117
Copyright
© 1978 American Society of Civil Engineers.
History
Published in print: Feb 1978
Published online: Feb 3, 2021
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Affiliations
Dhanjoo N. Ghista
Biomedical Research Division, NASA, Ames Research Center, Moffett Field, Calif.
K.B. Chandran
Research Assoc., Biomechanics Lab., Tulane Medical School, New Orleans, La.
Gautam Ray
Asst. Prof., Dept. of Mech. Engrg., Southern Univ., Baton Rouge, La.
Helmut Reul
Helmholtz Inst. an der RWTH Aachen Goethestr., Aachen, West Germany
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