Research Article
Jun 1977
Photodynamic Inactivation of Infectious Agents
Authors: M. Floyd Hobbs, M.ASCE, Jean S. Lennon, Joseph L. Melnick, Craig Wallis, and Charles P. GerbaAuthor Affiliations
Publication: Journal of the Environmental Engineering Division
Volume 103, Issue 3
Abstract
The photodynamic inactivation of poliovirus by use of the photoreactive dye methylene blue at pH 10 and monochromatic lights was investigated on a continuous flow basis. The photodynamic inactivation process was effective for virus inactivation in clarified wastewater and requires various unit operations that are inherent to both the tertiary treatment of secondary effluent for phosphorus and ammonia removal and for the physical-chemical treatment of sewage. The process can be used in existing physical-chemical waste treatment plants, secondary waste treatment plants where tertiary treatment for nutrient and improved carbon removals are of concern, and water treatment plants where the lime-softening process is used for water purification. Photodynamic inactivation rates for poliovirus using methylene blue at pH 10 were sensitive to heat during sensitization and subsequent irradiation.
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Published In
Journal of the Environmental Engineering Division
Volume 103 • Issue 3 • June 1977
Pages: 459 - 472
Copyright
© 1977 American Society of Civil Engineers.
History
Published in print: Jun 1977
Published online: Feb 11, 2021
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Authors
Affiliations
M. Floyd Hobbs, M.ASCE
Sr. Chemist; Environmental Engrg. Lab., FMC Corp., Santa Clara, Calif.
Jean S. Lennon
Chemist; Central Engrg. Labs., FMC Corp., Santa Clara, Calif.
Joseph L. Melnick
Prof. and Chmn.; Dept. of Virology and Epidemiology, Baylor Coll. of Medicine, Houston, Tex.
Craig Wallis
Prof.; Dept. of Virology and Epidemiology, Baylor Coll. of Medicine, Houston, Tex.
Charles P. Gerba
Asst. Prof.; Dept. of Virology and Epidemiology, Baylor Coll. of Medicine, Houston, Tex.
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