TECHNICAL NOTES
Dec 27, 2010

Pharmaceutical Residues in Wastewater Treatment Plants and Surface Waters in Bangkok

Publication: Journal of Hazardous, Toxic, and Radioactive Waste
Volume 16, Issue 1

Abstract

Pharmaceutical residues are increasingly found in wastewater treatment plant effluents and river water in very low concentrations at nanograms per liter levels in many countries. In this study, samples were collected from seven wastewater treatment plants (WWTPs) and downstream surface waters in Bangkok, Thailand during July and October 2009 and January 2010. Solid phase extraction (SPE) followed by high-pressure liquid chromatography-mass spectrometry-mass spectrometry (HPLC/MS/MS) technique were used to detect eight pharmaceuticals including caffeine, acetaminophen, roxithromycin, ciprofloxacin, trimethoprim, lincomycin, enrofloxacin, and erythromycin. Levels of pharmaceutical residues in the influents on average were the highest for caffeine ( 9,052ng/L ), followed by acetaminophen ( 8,630ng/L ), and roxithromycin ( 235ng/L ). The same three pharmaceuticals showed the top three levels in the effluents (caffeine: 797ng/L , acetaminophen: 92ng/L , and roxithromycin: 50ng/L ). The concentration of caffeine was also the highest in downstream surface water samples ( 2,393.4ng/L ). Acetaminophen ( 839.3ng/L ) and roxithromycin ( 54.7ng/L ) were at the second and third highest levels. Caffeine and acetaminophen in WWTP effluents were at very low levels compared with the influent concentrations.

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Acknowledgments

This study was supported by research funding from the Faculty of Engineering, Mahidol Univ., Thailand; Dept. of Environmental Toxicology, School of Public Health, Seoul National Univ., and School of Human and Environmental Science, Eulji Univ., Republic of Korea.

References

Boyd, G. R., Reemtsma, H., Grimm, D. A., and Mitra, S. (2003). “Pharmaceuticals and personal care products (PPCPs) in surface and treated waters of Louisiana, USA and Ontario, Canada.” Sci. Total Environ., 311(1–3), 135–149.
Boyd, G. R., Palmeri, J. M., Zhang, S., and Grimm, D. A. (2004). “Pharmaceuticals and personal care products (PPCPs) and endocrine disrupting chemicals (EDCs) in stormwater canals and Bayou St. John in New Orleans, Louisiana, USA.” Sci. Total Environ., 333(1–3), 137–148.
Choi, K., et al. (2008). “Seasonal variations of several pharmaceutical residues in surface water and sewage treatment plants of Han River, Korea.” Sci. Total Environ., 405(1–3), 120–128.
Daughton, C. G. (2004). PPCPs in the environment: Future research—Beginning with the end always in mind, Chapter 33, 2nd Ed., Springer, New York, 463–495.
Heberer, T. (2002a). “Tracking persistent pharmaceutical residues from municipal sewage to drinking water.” J. Hydrol. (Amsterdam), 266(3–4), 175–189.
Heberer, T. (2002b). “Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: A review of recent research data.” Toxicol. Lett., 131(1–2), 5–17.
Hignite, C., and Azarnoff, D. L. (1977). “Drugs and drug metabolites as environmental contaminations: Chlorophenoxyisobutyrate and salicylic acid in sewage water effluent.” Life Sci., 20(2), 337–341.
Jjemba, P. K. (2006). “Excretion and ecotoxicity of pharmaceuticals and personal care products in the environment.” Ecotox. Environ. Safe., 63(1), 113–130.
Kasprzyk-Hordern, B., Dinsdale, R. M., and Guwy, A. J. (2009). “The removal of pharmaceuticals, personal care products, endocrine disruptors, and illicit drugs during wastewater treatment and its impact on the quality of receiving waters.” Water Res., 43(2), 363–380.
Nasu, M., Goto, M., Kato, H., Oshima, Y., and Tanaka, H. (2001). “Study on endocrine disrupting chemicals in wastewater treatment plants.” Water Sci. Technol., 43(2), 101–108.
Peng, X., Yu, Y., Tang, C., Tan, J., Huang, Q., and Wang, Z. (2008). “Occurrence of steroid estrogens, endocrine-disrupting phenols, and acid pharmaceutical residues in urban riverine water of the Pearl River Delta, South China.” Sci. Total Environ., 397(1–3), 158–166.
Sipma, J., et al. (2010). “Comparison of removal of pharmaceuticals in MBR and activated sludge systems.” Desalination, 250(2), 653–659.
Suarez, S., Carballa, M., Omil, F., and Lema, J. M. (2008). “How are pharmaceutical and personal care products (PPCPs) removed from urban wastewater?” Rev. Environ. Sci. Biotechnol., 7(2), 125–138.
Ternes, T. A., et al. (2003). “Ozonation: A tool for removal of pharmaceuticals, contrast media, and musk fragrances from wastewater?” Water Res., 37(8), 1976–1982.
Zwiener, C., and Frimmel, F. H. (2000). “Oxidative treatment of pharmaceuticals in water.” Water Res., 34(6), 1881–1885.

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Go to Journal of Hazardous, Toxic, and Radioactive Waste
Journal of Hazardous, Toxic, and Radioactive Waste
Volume 16Issue 1January 2012
Pages: 88 - 91

History

Received: Jun 1, 2010
Accepted: Dec 23, 2010
Published online: Dec 27, 2010
Published in print: Jan 1, 2012

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Authors

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Ying Li, Ph.D. [email protected]
Formerly, Masters Student, Environmental Engineering Program, Dept. of Civil Engineering, Faculty of Engineering, Mahidol Univ., 25/25, Putthamonthon 4 Road, Salaya, Nakhorn Pathom 73170, Thailand. E-mail: [email protected]
Ranjna Jindal, Ph.D. [email protected]
Visiting Professor, Dept. of Civil Engineering, Faculty of Engineering, Mahidol Univ., 25/25, Putthamonthon 4 Road, Salaya, Nakhorn Pathom 73170, Thailand (corresponding author). E-mail: [email protected]
Kyungho Choi, Ph.D. [email protected]
Associate Professor, School of Public Health, Seoul National Univ., Republic of Korea. E-mail: [email protected]
Young Lim Kho [email protected]
Associate Professor, School of Human and Environmental Science, Eulji Univ., Republic of Korea. E-mail: [email protected]
Pura Garcia de Bullen [email protected]
Process Operations Chemist, Biofine Technology, LLC, Vassalboro, ME 04989; formerly, Masters Student, Environmental Engineering Program, Dept. of Civil Engineering, Faculty of Engineering, Mahidol Univ., Salaya, Nakhon Pathom 73170, Thailand. E-mail: [email protected]

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