Stress Deformation and Fluid Pressure of Bone Specimens under Cyclic Loading
Publication: Journal of Engineering Mechanics
Volume 135, Issue 5
Abstract
Cyclic loading has been known to induce fluid flow and thus mechanotransduction in bones. In the past, four-point bending tests have been used exclusively in studying fluid flow in bones. In order to better understand the mechanism of deformation and fluid flow under loading, compression tests were done on trabecular bone specimens under drained and undrained conditions. In the drained tests, the volume change was observed, whereas in the undrained tests, excess pore fluid pressure was measured. Cyclic loading tests were conducted in addition to monotonic loading tests to observe the permanent volume change or excess pore fluid pressure with loading cycles. A fast loading rate gave a sharp rise in the excess fluid pressure compared to a slow loading rate. The strength and stiffness of the specimens appeared to deteriorate with an increased speed of loadings, but there was no appreciable difference between the results obtained from drained and undrained tests. The drained and undrained tests as described allowed a better understanding of bone behavior under loadings for a coupled stress-flow analysis.
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Acknowledgments
This study is based upon works supported by the National Science Foundation under Grant No. NSFCMS-0510490, awarded to H. I. Ling, L. Wang, and M. L. Moss, with Dr. Ken Chong as Program Director. The writers appreciated the collaboration with Professor Edward Guo of the Department of Biomedical Engineering, Columbia University, with access to his bone cutting facilities. The first writer would also like to thank Professor Van C. Mow for his interactions through the seminars and thesis committees, and to Professor S. C. Cowin for his New York Bone Seminar Series. This paper is dedicated to the late Professor Melvin L. Moss, one of the co-PIs of this project, who passed away on June 25, 2006.
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Information & Authors
Information
Published In
Journal of Engineering Mechanics
Volume 135 • Issue 5 • May 2009
Pages: 375 - 381
Copyright
© 2009 ASCE.
History
Received: Jul 9, 2007
Accepted: Sep 26, 2008
Published online: May 1, 2009
Published in print: May 2009
Notes
Note. Associate Editor: Christian Hellmich
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